The impacts of Ramadan intermittent fasting (RIF) on muscular capacity of patients with chronic hepatitis B (CHB)

Résumé :

Introduction. Although RIF is not recommended in patients with CHB, several patients insist to fast during Ramadan. The impacts of RIF on muscular capacity of patients with CHB have not been evaluated. Aim. To evaluate the impacts of RIF on muscle mass and maximal isometric contraction of patients with CHB but free from cirrhosis.

Methods. This was an experimental study performed during the 2021 Ramadan. Patients were Tunisian male adults followed for an untreated CHB (n=13). The following data were collected before-(BR), during-(DR) and after-(AR) Ramadan: weight, body mass index (BMI), muscle mass, body fat, body water percentage, handgrip strength, and back and leg muscle strength.

Results. This table exposes the data of patients during the three sessions.

Weight (kg)81.4±12.4880.5±13.080.0±12.8&0.004
BMI (kg/m2)25.9±3.925.6±4.125.2±3.3&0.001
Muscle mass (kg)40.1±2.6#38.7±2.7¥39.1±2.30.001
Body fat (kg)22.3±5.4#23.8±6.022.8±4.70.001
Body water (%)53.3±3.7#52.4±4.1¥53.1±3.30.001
Handgrip strength (kg)49.5±8.249.5±6.648.7±7.1NS
Back and leg muscle strength (kg)133.9±26.4124.3±16.8140.5±34.1NS
NS: not-significant. p-value: ANOVA. #: BR vs. DR; &: BR vs. AR; ¥: DR vs. AR

Discussion/Conclusion. Despite the changes due to RIF on body composition including muscle mass, which can be explicated by the deprivation of food and water during the day, no change in maximal muscle capacity was observed. The RIF did not affect the isometric contraction of the skeletal muscle. This assumes that RIF has no impact on the energy process during isometric voluntary contraction in viral liver damage.

Mots clés : Ramadan intermittent fasting (RIF); Chronic liver diseases; Isometric muscle strength; Maximal voluntary contraction.

Auteurs : Jihène BERGAOUI , Helmi BEN SAAD, Jihène BEN ABDALLAH , Imed LATIRI

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