Clinical Pathogenicity Prediction Of Histone 3 Family Component With An In-silico Screening Of H3.3A Gene In Human
Histone variant H3.3 is a member of the human histone H3 family, it is expressed in whole cell cycle phases. H3.3 histone is encoded by two genes named H3.3A (H3F3A) and H3.3B (H3F3B) located on chromosome 1 and chromosome 17 respectively [1-3].Several studies have shown the possible role of histones methylation and acetylation with cancer […]