Articles

Effect on involuntary muscle contraction on FNDC5/Irisin

Irisin that is a peptide derived from the transmembrane protein FNDC5 is secreted into the blood in response to muscle contraction. FNDC5 is also expressed by skeletal muscle cells but also by neurons. Recent studies support the idea that circulating irisin and cerebral FNDC5 are involved in the neuroplastic and pro-cognitive effects of aerobic endurance […]

COMPARATIVE STUDY OF RESTING ELECTROCARDIOGRAPHIC ASPECTS BETWEEN YOUNG TOP ATHLETES AND SEDENTARY SENEGALESE

Introduction: Intensive and prolonged practice of sport can induce cardiovascular and electrocardiographic changes. The aim of our study was to compare the electrocardiographic signs of rest between athletes and sedentary people.Material and methods: A descriptive and comparative cross-sectional study was carried out from July to October 2019 involving high-level athletes and sedentary people. They were […]

Selenium concentrations and antioxidant enzymes activities in rat during selenium deficiency and sodium selenite and selenium-enriched Spirulina supplementations.

Résumé : ISelenium is an essential trace element essential for human life mainly due to its antioxidant properties through selenoproteins such as glutathione peroxidase. Spirulina is a blue-green algae known for its nutritive, anti-inflammatory and antioxidant properties and could be enriched in selenium during its culture. We showed that a selenium deficiency led to a sharp […]

Assessment of vascular function in individuals with type 2 diabetes

Résumé : INTRODUCTION : In patients with type 2 diabetes (T2D), vascular complications are the main reason for impaired life expectancy, and diabetic nephropathy and retinopathy are the largest contributors to end-stage renal disease and blindness, respectively. The current study assessed vascular function in subjects with type 2 diabetes, using pulse wave velocity (PWV) technique, the reference standard […]

Muscle fiber plays a critical role in therapeutic response to glucocorticoids during myositis

Résumé : Introduction. Myositis are autoimmune diseases characterized by chronic inflammation of skeletal muscle and muscle weakness.Glucocorticoids (GC), the first line treatment of myositis, improve muscle strength, but recovery is partial and, chronically, they lead to steroid myopathy. Thus, myositis care has to be improved. GC effects are mediated by glucocorticoid receptor (GR), which is expressed […]